منابع مشابه
The pill. The controversy continues.
Oral contraceptives (OC) are, or perhaps more correctly, were, until recently, being taken by approximately 6.5 million women worldwide, which corresponds to approximately 6% of all women of reproductive age. OCs have been available since the early 1960s and there is substantial evidence to suggest that no single medication has had such a profound impact on our reproduction and social life as t...
متن کاملBeta-carotene: the controversy continues.
The three beta-carotene intervention trials: the Beta Carotene and Retinol Efficacy Trial (CARET), Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC), and Physician's Health Study (PHS) have all pointed to a lack of effect of synthetic beta-carotene in decreasing cardiovascular disease or cancer risk in well-nourished populations. The potential contribution of beta-carotene suppleme...
متن کاملCerebral metabolic rate in hypercapnia: controversy continues.
Thirty years ago, a publication by Seisjo, entitled ‘Cerebral metabolic rate in hypercarbia—a controversy’ summarized the current state of knowledge related to the influence of hypercapnia (increased pCO2) on cerebral metabolic rate of oxygen consumption (CMRO2) (Siesjo, 1980). Seisjo quoted a number of papers that provided controversial results ranging from reduced, to unchanged, to increased ...
متن کاملFish-oil supplementation: the controversy continues.
The fetal brain accumulates n–3 long-chain polyunsaturated fatty acids (LCPUFAs), especially DHA, rapidly in the second half of pregnancy. Western diets have changed to a relatively high n–6:n–3 fatty acid ratio largely because of increased consumption of vegetable oils. Modern diets also provide less fish, the main source of DHA, than recommended in pregnancy. This may be of concern as higher ...
متن کاملDrug safety and salmeterol: the controversy continues.
Since their introduction in the 1960s, inhaled -agonists have been celebrated for their ability to offer dramatic relief of symptoms for persons with asthma. However, they have engendered considerable controversy. Early indications suggested that higher doses of some of the shortacting -agonists were associated with higher fatal and near-fatal asthma-related events (1). Further research suggest...
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ژورنال
عنوان ژورنال: Nature
سال: 1988
ISSN: 0028-0836,1476-4687
DOI: 10.1038/335200b0